The conference focuses on a broad range of research challenges in the field of simulation, modeling and analysis, addressing current and future trends in simulation techniques, methods, models, practices and software and tools. The conference is dedicated to fostering interdisciplinary collaborative research in these areas and across a wide spectrum of application domains. Building on the success of the previous editions, this year’s edition will provide an exciting forum for interaction among academic and industry researchers together with practitioners from both the modeling and simulation community, the emulation community, the development community, and the different user communities.