For the past fourteen years, the International ISC (Iranian Society of Cryptology) Conference on Information Security and Cryptology (ISCISC) has been the flagship conference in information security and cryptology. The 12th ISCISC conference is organized by the University of Guilan in co-operation with the Iranian Society of Cryptology. The conference will be held in the University of Guilan, Rasht, Iran from 2-4 September 2015. The objective of ISCISC’2015 is to bring together researchers, engineers and practitioners interested in various aspects of information security and cryptology. The conference aims to provide a forum for academicians, engineers, specialists, and students from all around the world to meet and discuss the latest developments in theory, emerging technologies, and progress in standards, services and their applications in various areas of information security. ISCISC’2015 encourages researchers, developers and practitioners to submit their original papers, and organize workshops on various new emerging topics. Industrial exhibitions are held in conjunction with the main conference. Keynote/plenary talks and panel discussions are other conference highlights.