We solicit high-quality original research papers (including significant work-in-progress) on any aspect of bioinformatics, biomedicine and healthcare informatics. New computational techniques and methods in machine learning; data mining; text analysis; pattern recognition; knowledge representation; databases; data modeling; combinatorics; stochastic modeling; string and graph algorithms; linguistic methods; robotics; constraint satisfaction; data visualization; parallel computation; data integration; modeling and simulation and their application in life science domain are especially encouraged. Relevant topics include but are not limited to:

1. Genomics and Molecular Structure, Function and Evolution

a. Next-Gen Sequencing and Metagenomics
b. Evolution, Phylogeny, Comparative Genomics
c. SNPs and haplotype analysis, GWAS
d. Protein/RNA Structure, Function and Interactions

2. Computational Systems Biology

a. Transcriptomics - Microarray Data Analysis
b. Gene Regulation, Alternative Splicing, Network/Pathway Analysis
c. Proteomics, PTMs, Metabolomics
d. Epigenomics, non-coding RNA analysis, DNA methylation analysis

3. Medical Informatics and Translational Bioinformatics

a. Biomedical Intelligence, Clinical Data Analysis, and Electronic Health Record
b. Biomedical Signal/Image Analysis
c. Genome-Phenome Analysis
d. Biomarker Discovery

4. Cross-Cutting Computational Methods and Bioinformatics Infrastructure

a. Biomedical Text Mining and Ontologies
b. Biological Data Mining and Visualization
c. Computational Modeling and Data Integration
d. High Performance Computing

5. Healthcare Informatics

a. Healthcare knowledge representation & reasoning
b. Health data acquisition, analysis and mining
c. Healthcare information systems
d. Clinical Decision Support and Informatics