These days, genome sequencing is becoming cheaper and more accessible by the hour. This wealth of human DNA sequence data offers insight into genomic structure and organization as well as clues to how disease states like cancer alter and are altered by DNA. This meeting will look at interpreting this information, appreciating its implications for basic cellular mechanisms and using this resource to inform therapies to promote human health. Two fields are uniquely positioned to foster this process – human genetics and chemical biology, and this meeting will highlight the growing intersections between the fields. Speakers from diverse disciplines will present recent advances in human genome analysis with an emphasis on disease states, look at how genetics informs basic cell biology and how it is transforming medicine. They will highlight recent progress in using chemical approaches to develop small molecule tools and drug discovery leads that will aid in translating the language of genetics into the language of pharmacology and medicine. The meeting aims to encourage collaboration between the fields and form a community, speaking a shared language that can drive discovery.

Session topics will include:

•Language of Chemistry
•Language of Genetics
•Moving from Genetics to Targets
•Bridging from Targets to Drugs
•The Frontier for Discovery